| Ingredients | AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) |
|---|---|
| Storage | Sealed, protected from light, store frozen at -20°C, avoid repeated freeze-thaw cycles |
| Shelf life | 24 months |
| SKU | Content / specification | Pack | Price | Availability |
|---|---|---|---|---|
| AR50 | 50mg | 10 vials | $89.00 | In stock |
Research use and intended-use limits
Research reagents are for laboratory and in-vitro research only. Not for human use.
Research reagents are not supplied as medicines and must not be used for diagnosis, treatment, prevention, clinical procedures or self-medication. Product information must not be used as administration or dosing guidance.
For accessories and consumables, follow their own specifications and documented intended use.
Description
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine, is a synthetic AMP analog that acts as a potent activator of AMPK (AMP-activated protein kinase). It mimics low energy states in cells, promoting glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and endurance enhancement. AICAR is widely researched for its potential to improve metabolic function, fat loss, exercise performance, and insulin sensitivity. It is commonly referred to as “exercise in a pill” due to its ability to activate exercise-related metabolic pathways. It is typically used via injection in research settings and remains an investigational compound. This content is for research purposes only and is provided solely for reference. It must not be interpreted as health, clinical, or legal advice or guidance.
Effects
Activates AMPK and promotes fat oxidation; inhibits fatty acid synthesis; improves insulin sensitivity; increases glucose uptake; enhances mitochondrial function; reduces hepatic gluconeogenesis
Usage
The typical research dosage is 50-100 mg/kg/day by intraperitoneal injection, or by oral administration. Specific usage should be determined according to product specifications and professional guidance; consultation with a specialist in the relevant field is recommended.
Suitable for
Individuals seeking fat loss; patients with metabolic syndrome; adjunct support for type 2 diabetes (under research); athletes (note the possibility of banned substances)
Not suitable for
Pregnant women; breastfeeding women; children; individuals with hepatic or renal impairment; individuals allergic to AICAR or any of its components; caution is required in patients taking blood glucose-lowering medications
Questions about AICAR
What is the intended use of AICAR?
Research reagents are intended solely for laboratory and in-vitro research. Suitability for a particular experiment must be assessed using the exact specification and available documentation. Accessories and consumables must be used according to their own specifications and documented intended use.
Can research reagents be used by or administered to people?
No. Research reagents are not for human use, diagnosis, treatment, prevention, clinical procedures or self-medication. A research-use label does not authorize use in people.
How can I verify the identity of AICAR?
No CAS number is published on this page. Do not infer the material's identity from its name. Request identification details and documentation for the exact product from the supplier.
Is a certificate of analysis (COA) available for AICAR?
No COA is currently published on this page in the selected language. Ask the supplier about documents for the exact batch before use; availability is not guaranteed. A COA does not establish safety for human use or medical approval.
Does a purity result or COA establish safety for human use?
No. A reported purity result describes the sample and test recorded in the document. It does not establish safety for human use, clinical suitability or medical approval. Review the method, batch identity and relevant specifications for your laboratory work.
How should AICAR be stored and handled?
The storage information published for this product is: Sealed, protected from light, store frozen at -20°C, avoid repeated freeze-thaw cycles. Confirm the batch-specific storage and handling instructions with the supplier before receipt and use.
Does an available shipping option mean the product can be imported?
No. A shipping quote at checkout is not import authorization. Before ordering, verify whether the exact product and quantity are admissible at the destination and what purchasing, import, documentation and use requirements apply.
What should I confirm before procurement?
Match the SKU, specification and batch or lot identifier to your research requirements. Request any required COA and safety documentation and confirm availability before ordering; documents are not guaranteed to be available. Also verify applicable requirements at the destination.
