Description
PNC-27 is a synthetic peptide derived from the p53 protein, exhibiting potential anti-tumor activity by selectively binding to cancer cell membranes and inducing apoptosis.
Effects
Selectively induces apoptosis in cancer cells; inhibits tumor cell proliferation; competes with Hdm2 protein to restore p53 function; low toxicity to normal cells; may enhance chemotherapy sensitivity.
Usage
Reconstitute lyophilized powder with sterile water for injection or normal saline. Recommended dose: 10-20 mg/day, administered subcutaneously or intravenously. Treatment cycle is typically 28 days or as adjusted by physician.
Suitable for
Patients with various cancers (especially p53 wild-type tumors); candidates for adjuvant therapy or combination chemotherapy.
Not suitable for
Individuals allergic to PNC-27 or any components; pregnant or breastfeeding women; severe hepatic or renal impairment; patients with autoimmune diseases.
Ingredients
PNC-27 (synthetic peptide)
Storage
Store lyophilized powder at -20°C, protected from light. After reconstitution, refrigerate at 2-8°C and use within 24 hours. Avoid repeated freeze-thaw cycles.
Shelf life
24 months
